WeboRGs and mitotic somal translocation - a role in development and disease. Curr Opin Neurobiol. 2024 02; 42:61-67. Ostrem B, Di Lullo E, Kriegstein A. PMID: 27978479; PMCID: PMC5638645. View in: PubMed Mentions: 25 Fields: Bio Biology Neu Neurology Translation: Humans Cells Control of outer radial glial stem cell mitosis in the human brain.
Adult Human Glioblastomas Harbor Radial Glia-like Cells.
WebHere, we identify EGFR-expressing “Pre-OPCs” that originate from outer radial glial cells (oRGs) and undergo mitotic somal translocation (MST) during division. oRG-derived Pre-OPCs provide an additional source of human cortical oligodendrocyte precursor cells (OPCs) and define a lineage trajectory. WebEvolutionary expansion of the human neocortex is partially attributed to a relative abundance of neural stem cells in the fetal brain called outer radial glia (oRG). oRG cells display a characteristic division mode, mitotic somal translocation (MST), in which the soma rapidly translocates toward the cortical plate immediately prior to cytokinesis. cleaning service invoice form
Patterns of neuronal migration in the embryonic cortex
Web2 jan. 2024 · Using live time-lapse imaging of primary resected tumors, we discover that tumor-derived oRG-like cells undergo characteristic mitotic somal translocation behavior … Web23 okt. 2024 · Human autosomal recessive primary microcephaly (MCPH) is a heterogeneous disorder with mutations in twelve genetic loci ( MCPH1 – 12) (Faheem et al., 2015; Woods et al., 2005 ). Mutations in the Aspm gene (abnormal spindle-like microcephaly-associated) at the MCPH5 locus are expected to be the most common … Web20 nov. 2024 · Using live time-lapse imaging of primary resected tumors, we discover that tumor derived oRG-like cells undergo characteristic mitotic somal translocation … cleaning service job description