Myh6 mercremer
WebMyh6-MerCreMer+/+ AKAP2fl/fl mice. The presence of the MerCreMer transgene was confirmed by PCR, using the Cre-F sense primer (ATACCGGAGATCATGCA AGC) and … Web22 dec. 2024 · Myh6-MerCreMer Tg/0 mice were crossbred with Cul7 flox/flox mice to obtain Cul7 flox/flox Myh6-MerCreMer Tg/0 and Cul7 +/+ Myh6-MerCreMer Tg/0 control …
Myh6 mercremer
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Web27 nov. 2024 · In this system, Myh6-MerCreMer:R26R-Confetti-labelled cells and their daughter cells could express one of four different fluorescent reporters: nGFP, YFP, RFP or mCFP. Fig. 4 Gel–miR-302-induced... Web5 jan. 2024 · Myh6-Mcm: Myosin heavy chain 6-MerCreMer; F/M: female/male; HR: heart rate; bpm: beats per minute; AWT: anterior wall thickness; LVPWT: left ventricular …
Web1 jul. 2011 · To circumvent this limitation, a widely used inducible cardiac-specific model, Myh6 -MerCreMer (Cre), using tamoxifen (TAM) to activate Cre has been developed. The current study examined cardiac function in Cre-positive C57B/J6 mice exposed to one, three, or five daily doses of a 40 mg/kg TAM to induce Cre activity specifically in the heart. WebMoreover, the number of PH3 + cardiomyocytes was significantly higher in Myh6 mercremer:R26R-miR302-367 Tg/+ hearts than in Myh6 mercremer controls 3 weeks …
WebMice bearing either floxed Ulk1 or floxed Ulk2 alleles were crossed with transgenic mice expressing a tamoxifen-inducible Cre recombinase (Myh6-MerCreMer). Gene … Web1 jul. 2024 · Genetic fate mapping was performed using an inducible, cardiomyocyte specific Myh6-MerCreMer mouse model, crossed with a LacZ reporter. A single large dose of tamoxifen successfully labelled 70–80% of cardiomyocytes when administered at P0, and was followed by apical resection at P2.
Web7 mrt. 2024 · Furthermore, we generated Myh6-merCremer;Thra DN/+ mice and induced DN-TRα expression around the perinatal window (fig. S10). Increased prevalence of diploid proliferative cardiomyocytes was also observed in these mutants (fig. S10).
Web005650 STOCK A1cf Tg(Myh6-cre/Esr1*)1Jmk /J The alpha-MHC-MerCreMer (αMHC-MerCreMer) transgene has the mouse cardiac-specific alpha-myosin heavy chain … cuffed work jeansWeb15 dec. 2012 · Neither the heterozygous Myh6-MerCreMer/LepR flox/WT nor the Myh6-MerCreMer mice exhibited any overt signs of heart failure as observed in the homozygous LepR KO mice. Heart weight-to-body weight ratio was significantly elevated in Lepr KO compared with control mice and averaged 7.4 ± 0.4 vs. 5.6 ± 0.2 mg/g. eastern channelWeb23 jul. 2015 · These results suggest that the new Myh6 (MerCreMer/+) mouse can serve as a robust tool to dissect the roles of genes in heart development and function. … eastern chamber of commerce lake county ohioWebIn this study, we generated a Myh6-Cre knockin mouse model by inserting the IRES-Cre-wpre-polyA cassette between the translational stop codon and the 3' untranslated region of the endogenous Myh6 gene. By crossing knockin mice with the Rosa26 reporter lines, we found that Myh6-Cre targeted cardiomyocytes at the embryonic and postnatal stages. eastern chamber of commerce peiWeb20 sep. 2024 · Myh6, also known as αMHC, Myhc and Myhca, encodes the cardiac muscle specific protein, alpha-myosin heavy chain, which is dynamically expressed in … eastern chb llcWeb19 jan. 2024 · Myh6-MerCreMer +; Tead1 W/W mice treated with PBS (Control + PBS) or Nec (Control + Nec) served as additional controls. b Echocardiographic measurement of … eastern channel routen dfdsWebProduct Specs; Item A1cf Mouse shRNA Plasmid (Locus ID 69865); Company OriGene Technologies; Price Pricing Info Supplier Page View Company Product Page; Catalog … eastern channel pile light